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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COL7A1 All Species: 12.73
Human Site: S2421 Identified Species: 23.33
UniProt: Q02388 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02388 NP_000085.1 2944 295220 S2421 E M G Q P G P S G E R G L A G
Chimpanzee Pan troglodytes XP_001158576 2944 295343 S2421 E M G Q P G P S G E R G L A G
Rhesus Macaque Macaca mulatta XP_001097876 2888 289235 S2365 E M G Q P G P S G E R G L A G
Dog Lupus familis XP_850954 1689 162558 P1360 G P Q G F S G P Q G A P G Q T
Cat Felis silvestris
Mouse Mus musculus Q63870 2944 295214 V2412 E T G Q P G P V G E R G L A G
Rat Rattus norvegicus P02466 1372 129546 L1043 G L P G L A G L H G D Q G A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506111 2993 304674 S2274 Q P G P P G P S G E R G L I G
Chicken Gallus gallus P32018 1888 202649 A1559 G S P G R D G A Q G Q R G L P
Frog Xenopus laevis Q91717 1486 142245 G1157 A G D Q G A T G P A G P A G P
Zebra Danio Brachydanio rerio A0MSJ1 1658 168231 D1329 G F K G Q P G D A G E Q G F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08120 1779 174282 G1450 D G R D G T P G L P G Q K G E
Honey Bee Apis mellifera XP_392097 1913 189642 P1584 P K G D R G F P G P V G P P G
Nematode Worm Caenorhab. elegans P17139 1759 171068 P1429 L D G L P G R P G R E G L P G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 92.3 28.3 N.A. 84.3 26.7 N.A. 49.5 22.3 27.2 26.4 N.A. 28.3 29 29.4 N.A.
Protein Similarity: 100 99.3 94 36 N.A. 89.5 31.7 N.A. 61.4 32.6 34.3 35.7 N.A. 37.4 37.7 36.5 N.A.
P-Site Identity: 100 100 100 0 N.A. 86.6 6.6 N.A. 73.3 0 6.6 0 N.A. 6.6 33.3 46.6 N.A.
P-Site Similarity: 100 100 100 0 N.A. 86.6 13.3 N.A. 80 13.3 6.6 0 N.A. 13.3 33.3 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 16 0 8 8 8 8 0 8 39 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 16 0 8 0 8 0 0 8 0 0 0 0 % D
% Glu: 31 0 0 0 0 0 0 0 0 39 16 0 0 0 8 % E
% Phe: 0 8 0 0 8 0 8 0 0 0 0 0 0 8 0 % F
% Gly: 31 16 54 31 16 54 31 16 54 31 16 54 31 16 54 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 8 8 0 8 8 0 0 8 8 0 0 0 47 8 0 % L
% Met: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 16 16 8 47 8 47 24 8 16 0 16 8 16 31 % P
% Gln: 8 0 8 39 8 0 0 0 16 0 8 24 0 8 0 % Q
% Arg: 0 0 8 0 16 0 8 0 0 8 39 8 0 0 0 % R
% Ser: 0 8 0 0 0 8 0 31 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _